Iodosulfuron

Iodosulfuron

SCHEMBL7589891

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COc1nc(C)nc(NC(=O)NS(=O)(=O)c2cc(I)ccc2C(=O)O)n1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TTR P02766 1/20 0.38
PPOX P50336 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
CCR6 P51684 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
TBXA2R P21731 4/20 0.31
KDM4E B2RXH2 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PYGL P06737 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodosulfuron SCHEMBL7586812 0.95 KMT2A (0.44) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7582225 0.94 KMT2A (0.39) MEN1KMT2ATTRPPOXTDP1
Iodosulfuron SCHEMBL7590195 0.93 MEN1 (0.38) MEN1KMT2ATTRPPOXTDP1
Fomesafen SCHEMBL7588310 0.93 MEN1 (0.40) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7578234 0.92 KDM4E (0.38) MEN1KMT2ATTRPPOXTDP1
Lactofen SCHEMBL7579310 0.91 MEN1 (0.37) MEN1KMT2ATTRPPOXTDP1
Iodosulfuron SCHEMBL7587442 0.91 MEN1 (0.46) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7579243 0.90 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Acifluorfen SCHEMBL7584724 0.89 KMT2A (0.45) MEN1KMT2ATTRPPOXTDP1
Logran SCHEMBL7589682 0.89 KMT2A (0.34) MEN1KMT2ATTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.