Glycinebetaine

Glycinebetaine

SCHEMBL75899

C[N+](C)(C)CC(=O)[O-].NCC(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

BHMTBHMT2

The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
APEX1 P27695 1/20 0.50
GLRA1 P23415 1/20 0.48
SLC6A9 P48067 1/20 0.48
OR51E2 Q9H255 1/20 0.48
CPT2 P23786 1/20 0.39
CPT1A P50416 1/20 0.39
SLC22A16 Q86VW1 1/20 0.37
BBOX1 O75936 6/20 0.32
MAPT P10636 1/20 0.32
GABRR1 P24046 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
HRH1 P35367 1/20 0.31
KMT2A Q03164 1/20 0.31
CRAT P43155 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycinebetaine SCHEMBL618945 0.98 TSHR (0.50) TSHRALDH1A1LMNAAPEX1GLRA1
Glycinebetaine SCHEMBL18301505 0.98 TSHR (0.50) TSHRALDH1A1LMNAAPEX1GLRA1
Glycinebetaine SCHEMBL21084282 0.90 TSHR (0.43) TSHRALDH1A1LMNAAPEX1GLRA1
Glycinebetaine SCHEMBL4541516 0.87 TSHR (0.40) TSHRALDH1A1LMNAAPEX1GLRA1
Glycinebetaine SCHEMBL20298304 0.87 TSHR (0.40) TSHRALDH1A1LMNAAPEX1GLRA1
Glycinebetaine SCHEMBL7521843 0.85 TSHR (0.43) TSHRALDH1A1LMNAAPEX1CPT2
Glycinebetaine SCHEMBL6673018 0.85 TSHR (0.50) TSHRALDH1A1LMNAAPEX1CPT2
Glycinebetaine SCHEMBL9281697 0.85 TSHR (0.55) TSHRALDH1A1LMNAAPEX1CPT2
Glycinebetaine SCHEMBL9116728 0.85 TSHR (0.48) TSHRALDH1A1LMNAAPEX1CPT2
Glycinebetaine SCHEMBL3497624 0.85 TSHR (0.46) TSHRALDH1A1LMNAAPEX1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26911 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094699-A Method for coupling dialkylamines and polypeptides 2026-05-26 CN claimed
US-12618028-B2 Fermented and esterified molasses LESAFFRE ET COMPAGNIE (FR) 2026-05-05 US claimed
US-20260115127-A1 Cosmetic Composition GIVAUDANA SA (CH) 2026-04-30 US claimed
WO-2026087898-A1 CONTROLLED RELEASE OF OSMOPROTECTANT AGENTS FROM CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2026-04-30 WO claimed
US-12605320-B2 Photoprotective composition comprising a glycine betaine derivative SURFACTGREEN (FR) 2026-04-21 US claimed
EP-4721659-A2 ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS DexCom, Inc. (US) 2026-04-08 EP claimed
US-12593843-B2 Method for improving seed germination and/or plant tolerance to environmental stress DANSTAR FERMENT AG (CH) 2026-04-07 US claimed
EP-4344632-B1 ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS DEXCOM INC (US) 2026-04-01 EP claimed
US-12584101-B2 Compositions and method of use for H5 competent Bifidobacterium longum subsp. Infantis INFINANT HEALTH, INC. (US) 2026-03-24 US claimed
CN-121574898-A Preparation method of agarose with low solidification temperature 大连富勒烯药业有限公司 2026-02-27 CN claimed
WO-1998030702-A2 POLYNUCLEOTIDES ENCODING CHOLINE MONOOXYGENASE AND PLANTS TRANSFORMED THEREWITH UNIVERSITY OF FLORIDA (US) 1998-07-16 WO claimed
WO-1998026081-A1 TRANSGENIC PLANTS HAVING INCREASED FREEZING AND CHOLINE TOLERANCE BUELOW LEIF (SE) 1998-06-18 WO claimed
EP-0806897-A1 OSMOLYTE REGULATOR A.B. TALL (HOLDINGS) PTY LTD. (AU) 1997-11-19 EP claimed
EP-0790772-A1 OSMOLYTE REGULATOR A.B. TALL (HOLDINGS) PTY LTD. (AU) 1997-08-27 EP claimed
WO-1996023413-A1 OSMOLYTE REGULATOR AB TALL (HOLDINGS) PTY. LTD. (AU) 1996-08-08 WO claimed
WO-1996014749-A1 OSMOLYTE REGULATOR AB TALL (HOLDINGS) PTY. LTD. (AU) 1996-05-23 WO claimed
EP-0474213-B1 Method for chromatographic purification of insulins HOECHST AG (DE) 1995-09-20 EP claimed
US-5245008-A PROCESS FOR THE PURIFICATION OF INSULINS BY CHROMATOGRAPHY HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-14 US claimed
US-4818268-A ENHANCING MUSHROOM GROWTH; PROTEIN CARRIER, PHOSPHOGLYCERIDE SPAWN MATE, INC. (US) 1989-04-04 US claimed
US-4122043-A BUILDERS, CHELATING OR SEQUESTERING AGENTS POLYTROL CHEMICAL CORPORATION (US) 1978-10-24 US claimed