Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CRAT | P43155 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL75899 | 0.90 | TSHR (0.52) | TSHRALDH1A1LMNAAPEX1GLRA1 | |
| Glycinebetaine SCHEMBL18301505 | 0.88 | TSHR (0.50) | TSHRALDH1A1LMNAAPEX1GLRA1 | |
| Glycinebetaine SCHEMBL618945 | 0.88 | TSHR (0.50) | TSHRALDH1A1LMNAAPEX1GLRA1 | |
| Glycinebetaine SCHEMBL4541516 | 0.81 | TSHR (0.40) | TSHRALDH1A1LMNAAPEX1GLRA1 | |
| Glycinebetaine SCHEMBL3513638 | 0.81 | TSHR (0.40) | TSHRALDH1A1LMNAAPEX1CPT2 | |
| Glycinebetaine SCHEMBL6894104 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNAAPEX1CPT2 | |
| Glycinebetaine SCHEMBL28110612 | 0.79 | TSHR (0.42) | TSHRALDH1A1LMNAAPEX1CPT2 | |
| Glycine SCHEMBL3674731 | 0.78 | GLRA1 (0.62) | TSHRLMNAAPEX1GLRA1SLC6A9 | |
| Glycine SCHEMBL20494486 | 0.78 | GLRA1 (0.62) | TSHRLMNAAPEX1GLRA1SLC6A9 | |
| Glycinebetaine SCHEMBL20298304 | 0.78 | TSHR (0.40) | TSHRALDH1A1LMNAAPEX1GLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339353-B2 | Acidic hard surface cleaner with glycine betaine ester | S.C. JOHNSON & SON, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20190203157-A1 | ACIDIC HARD SURFACE CLEANER WITH GLYCINE BETAINE ESTER | S. C. JOHNSON & SON, INC. (US) | 2019-07-04 | — | — | US | disclosed |