Ethyl Acetate

Ethyl Acetate

SCHEMBL7589907

CC(=O)O.CCOC(C)=O.O.c1ccncc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
LMNA P02545 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TSHR P16473 4/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CASP1 P29466 1/20 0.36
CDC7 O00311 2/20 0.35
DBF4 Q9UBU7 2/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL38324 0.98 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL7281476 0.98 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL902253 0.96 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL11661625 0.96 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL11599396 0.96 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL11222752 0.94 ALDH1A1 (0.54) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL27535761 0.94 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL27540812 0.94 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL11520158 0.93 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL11434031 0.92 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278072-B1 Method for synthesis of sialylated products using reversible sialylation HEALTH RESEARCH, INC. (US) 2012-10-02 US disclosed
WO-2001090309-A9 PEPTIDES THAT STIMULATE MYCOBACTERIAL GROWTH UNIV COLORADO STATE RES FOUND (US) 2002-12-12 WO disclosed
WO-2001090309-A2 PEPTIDES THAT STIMULATE MYCOBACTERIAL GROWTH COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2001-11-29 WO disclosed
US-5340802-A Central nervous system disorders ABBOTT LABORATORIES (US) 1994-08-23 US disclosed
EP-0449884-A4 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS 1991-10-30 EP disclosed
EP-0449884-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1991-10-09 EP disclosed
EP-0405506-A1 Tetrapeptide type-B CCK receptor ligands ABBOTT LABORATORIES (US) 1991-01-02 EP disclosed
US-4431635-A PEPTIDE ANALOGS OF LUTEINIZING HORMONE RELEASING HORMONE; GLANDULAR DISORDERS; ANTICARCINOGENIC AGENTS COY DAVID HOWARD 1984-02-14 US disclosed
US-4314998-A 6-Deoxyglucosamine-peptide derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-09 US disclosed