Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL7589907 | 0.98 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL902253 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL11599396 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL11661625 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL11222752 | 0.96 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL27540812 | 0.96 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL7281476 | 0.96 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL27535761 | 0.96 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL11434031 | 0.94 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Acetate SCHEMBL7067099 | 0.93 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1857602-A | Quality control method for vatility source preparation | ZHONGHUI PHARMACEUTICAL CO LTD (CN) | 2006-11-08 | — | — | CN | claimed |
| US-4316894-A | Antibiotic SF-1130-x3 3 substance and production and use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-02-23 | — | — | US | claimed |
| US-4160026-A | Antibiotics SF-1130-x1 and -x2 substances and production and use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1979-07-03 | — | — | US | claimed |
| CN-110372746-A | Method for synthesizing beta-aminophosphine oxide compound | 辽宁石油化工大学 | 2019-10-25 | — | — | CN | disclosed |
| US-20130149427-A1 | Method of Preparing Flour or Splits of Legume | Bühler AG (CH) | 2013-06-13 | — | — | US | disclosed |
| EP-2575479-A2 | METHOD OF PREPARING FLOUR OR SPLITS OF LEGUME | Bühler AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-8324177-B2 | Triterpene compositions and methods for use thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-12-04 | — | — | US | disclosed |
| WO-2011151096-A2 | METHOD OF PREPARING FLOUR OR SPLITS OF LEGUME | Bühler AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110294752-A1 | TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2011-12-01 | — | — | US | disclosed |
| EP-1079824-B1 | TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF | RES DEV FOUNDATION (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7985435-B2 | Triterpene compositions and methods for use thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2011-07-26 | — | — | US | disclosed |
| CN-86108977-A | N-amido glucuronide aglycone antibiotics A40926 family and aglycone antibiotics A40926 | — | 1988-04-27 | — | — | CN | disclosed |
| CN-85107903-A | Produce the method for antibiotic A40926 complex and pure factors PA.PB.A.B. and B0 | — | 1987-05-06 | — | — | CN | disclosed |
| US-4316894-A | Antibiotic SF-1130-x3 3 substance and production and use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-02-23 | — | — | US | disclosed |
| US-4160026-A | Antibiotics SF-1130-x1 and -x2 substances and production and use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4159981-A | CYCLIC POLYPEPTIDES, DEETHERIFICATION, DEESTERIFICATION | CIBA-GEIGY CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-3994871-A | Process for the manufacture of peptides containing cystine | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3966557-A | STREPTOMYCES | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3956260-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3934008-A | PEPTIDES, HYPOCALCAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294752-A1 | TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF | OSTC, ACACA, NFATC1 | MEN1 3958/4885ALDH1A1 2759/4885LMNA 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.