Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306060 | 0.91 | LMNA (0.47) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL30445192 | 0.87 | MAOB (0.46) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL7721868 | 0.87 | MAOB (0.46) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL12932024 | 0.86 | LMNA (0.45) | MAOBIDO1MAOAALDH1A1KDM4E | |
| SCHEMBL19298146 | 0.84 | IDO1 (0.44) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL4304431 | 0.82 | IDO1 (0.43) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL4791688 | 0.79 | MAOB (0.50) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL12900304 | 0.79 | MAPT (0.44) | MAOBIDO1MAOAALDH1A1KDM4E | |
| SCHEMBL28926584 | 0.78 | TOP2A (0.59) | MAOBIDO1MAOAALDH1A1TOP2A | |
| SCHEMBL496431 | 0.78 | MAOB (0.49) | MAOBIDO1MAOAALDH1A1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747448-B1 | Rigidized monomethine cyanine dyes | UNIV CARNEGIE MELLON (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0747448-A2 | Rigidized monomethine cyanine dyes | CARNEGIE-MELLON UNIVERSITY (US) | 1996-12-11 | — | — | EP | disclosed |