SCHEMBL7589965

SCHEMBL7589965

Cc1cc2cc(C(=O)O)c(C)cc2cc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.48
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47
GABRG3 Q99928 1/20 0.47
GABRQ Q9UN88 1/20 0.47
NOTUM Q6P988 1/20 0.46
KDM4E B2RXH2 4/20 0.45
HPGD P15428 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14626130 1.00 GPR35 (0.48) GPR35GABRPGABRDGABRA1GABRB1
SCHEMBL12446315 0.90 NOTUM (0.46) GPR35GABRPGABRDGABRA1GABRB1
SCHEMBL14627664 0.89 CSNK2A1 (0.48) GPR35KDM4EHPGDHSD17B10GAA
SCHEMBL14626128 0.89 CSNK2A1 (0.48) GPR35KDM4EHPGDHSD17B10GAA
SCHEMBL2778964 0.86 IDO1 (0.59) GPR35KDM4EHPGDHSD17B10ALDH1A1
SCHEMBL70135 0.86 KDM4E (0.54) GPR35GABRPGABRDGABRA1GABRB1
SCHEMBL69934 0.83 KDM4E (0.50) GPR35GABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL4352648 0.83 KDM4E (0.52) GPR35GABRPGABRDGABRA1GABRB1
SCHEMBL10746287 0.82 KDM4E (0.49) GPR35NOTUMKDM4EHPGDHSD17B10
SCHEMBL2400964 0.81 KDM4E (0.50) GPR35GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0988342-B1 PROCESS FOR CRYSTALLIZING BLENDS OF POLYETHYLENE TEREPHTHALATE AND POLYETHYLENE ISOPHTHALATE M & G POLIMERI ITALIA SPA (IT) 2002-10-23 EP disclosed
EP-0988342-A1 PROCESS FOR CRYSTALLIZING BLENDS OF POLYETHYLENE TEREPHTHALATE AND POLYETHYLENE ISOPHTHALATE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2000-03-29 EP disclosed
US-5919872-A Process for crystallizing blends of polyethylene terephthalate and polyethylene isophthalate SHELL OIL COMPANY (US) 1999-07-06 US disclosed
WO-1998056856-A1 PROCESS FOR CRYSTALLIZING BLENDS OF POLYETHYLENE TEREPHTHALATE AND POLYETHYLENE ISOPHTHALATE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1998-12-17 WO disclosed
EP-0105824-B1 POLYISOPHTHALATES AND COPOLYMERS THEREOF HAVING HIGH BARRIER PROPERTIES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-04-27 EP disclosed
US-4643925-A PACKAGING FOODS AND BEVERAGES, CANS AND BOTTLES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-02-17 US disclosed
EP-0105016-B1 POLYISOPHTHALATE AND COPOLYMERS THEREOF HAVING REDUCED CYCLIC DIMER CONTENT, AND A PROCESS FOR MAKING THE SAME THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-01-21 EP disclosed
EP-0103531-B1 POLYETHYLENE ISOPHTHALATE HAVING REDUCED CYCLIC DIMER CONTENT AND PROCESS THEREFOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-12-30 EP disclosed
US-4604257-A POLYESTERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-08-05 US disclosed
US-4482586-A Multi-layer polyisophthalate and polyterephthalate articles and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-11-13 US disclosed
US-4447595-A HAZE-FREE PACKAGING MATERIALS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-05-08 US disclosed
EP-0105824-A1 Polyisophthalates and copolymers thereof having high barrier properties THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-18 EP disclosed
EP-0105825-A2 Multi-layer polyisophthalate and polyterephthalate articles and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-18 EP disclosed
EP-0105016-A1 Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-04 EP disclosed
EP-0103531-A1 Polyethylene isophthalate having reduced cyclic dimer content and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-21 EP disclosed
EP-0102913-A2 Polyterephthalates having high clarity and process for making same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-14 EP disclosed
US-4424337-A Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-01-03 US disclosed
US-4418188-A PROTONIC ACID CATALYSTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-29 US disclosed
US-4403090-A Polyisophthalates and copolymers thereof having high barrier properties THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-09-06 US disclosed