Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16288916 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL28140639 | 0.73 | — | — | |
| SCHEMBL28140543 | 0.73 | — | — | |
| SCHEMBL3259762 | 0.71 | XDH (0.58) | XDHALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL9277814 | 0.71 | NPC1 (0.52) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL5746267 | 0.70 | TLR8 (0.48) | ALDH1A1KDM4ECYP3A4PTGS1TP53 | |
| SCHEMBL7555913 | 0.69 | XDH (0.56) | XDHALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL18394267 | 0.69 | XDH (0.43) | XDHALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL10571992 | 0.68 | XDH (0.46) | XDHALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL2886536 | 0.68 | XDH (0.46) | XDHALDH1A1MAPTGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080895-A2 | TREATMENT OF MALARIA WITH FARSENYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2002080895-A2 | TREATMENT OF MALARIA WITH FARSENYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |