Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587316 | 1.00 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL6508653 | 0.82 | TSHR (0.67) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL12341355 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL16406073 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL8921592 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATSHRMMP2 | |
| SCHEMBL7589072 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATSHRMMP2 | |
| SCHEMBL15000482 | 0.77 | TSHR (0.50) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL3268152 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNACA1TSHR | |
| SCHEMBL30381605 | 0.77 | TRPA1 (0.40) | LMNATSHRMMP2 | |
| Isopropyl Alcohol SCHEMBL29076646 | 0.76 | TSHR (0.71) | ALDH1A1LMNACA1TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| US-6057328-A | TREATING CONDITIONS RESULTING FROM HYPEROXIA, AND IN PARTICULAR, CONDITIONS RESULTING FROM THERAPEUTIC ADMINISTRATION OF OXYGEN COMPRISING ADMINISTERING XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5629423-A | Asymmetric synthesis of chiral secondary alcohols | CELL THERAPEUTICS, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |