Sugi Predict

Sugi Predict / Compounds / Bifenox

Bifenox

Bifenox

SCHEMBL7590199

CC1(C)CON(Cc2ccccc2Cl)C1=O.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.63
▸ MAPT P10636 6/20 0.40
▸ LMNA P02545 5/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ PLA2G1B P04054 2/20 0.40
▸ ATG4B Q9Y4P1 2/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ MEN1 O00255 7/20 0.39
▸ KMT2A Q03164 7/20 0.39
▸ TTR P02766 1/20 0.39
▸ PPOX P50336 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ HTT P42858 2/20 0.36
▸ EPHX2 P34913 1/20 0.35
▸ GSK3B P49841 1/20 0.35
▸ THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7587007 0.91 TDP1 (0.52) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL7580827 0.89 TDP1 (0.49) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL7577818 0.89 TDP1 (0.49) TDP1MAPTLMNAALDH1A1PLA2G1B
Acifluorfen SCHEMBL7586835 0.83 TDP1 (0.63) TDP1MAPTLMNAALDH1A1PLA2G1B
Clomazone SCHEMBL7585649 0.81 KMT2A (0.48) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL8541647 0.79 TDP1 (1.00) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL38816 0.79 TDP1 (1.00) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL30862569 0.79 TDP1 (1.00) TDP1MAPTLMNAALDH1A1PLA2G1B
Bifenox SCHEMBL28419037 0.78 TDP1 (0.98) TDP1MAPTLMNAALDH1A1PLA2G1B
Acifluorfen SCHEMBL7581714 0.77 MEN1 (0.52) TDP1MAPTLMNAALDH1A1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MAPT 1092/4885LMNA 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.