Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695700 | 0.90 | PTPN11 (0.47) | PTPN11LCKPLAUUSP2CA1 | |
| SCHEMBL8148281 | 0.84 | CA1 (0.52) | USP2CA1CA2CA12CA7 | |
| SCHEMBL9979782 | 0.84 | PTPN11 (0.64) | PTPN11LCKPLAUCA1CA2 | |
| SCHEMBL69025 | 0.84 | PTPN11 (0.68) | PTPN11LCKPLAUCA1CA2 | |
| SCHEMBL29365729 | 0.84 | PTPN11 (0.68) | PTPN11LCKPLAUCA1CA2 | |
| SCHEMBL5566033 | 0.83 | PLAU (0.64) | PTPN11LCKPLAUUSP2CA1 | |
| SCHEMBL3558563 | 0.82 | PLAU (0.59) | PTPN11LCKPLAUCA1CA2 | |
| SCHEMBL8732524 | 0.82 | PTPN11 (0.66) | PTPN11LCKPLAUCA1CA2 | |
| SCHEMBL709231 | 0.82 | LCK (0.62) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL9005203 | 0.81 | KDM4E (0.42) | PTPN11USP2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284369-B1 | 5- OR 6-ALKOXYCARBONYL-2,3-DICYANONAPHTHALENES AND PROCESS FOR PRODUCTION THEREOF | Hitachi Chemical Co., Ltd. (JP) | 1992-05-20 | — | — | EP | claimed |
| US-4833264-A | INTERMEDIATES FOR NAPHTHALOCYANINE DYES | HITACHI CHEMICAL CO., LTD. (JP) | 1989-05-23 | — | — | US | claimed |
| EP-0284369-A2 | 5- or 6-alkoxycarbonyl-2,3-dicyanonaphthalenes and process for production thereof | Hitachi Chemical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | claimed |
| JP-1006249-A | — | — | None | — | — | JP | disclosed |
| EP-0597389-B1 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5665875-A | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| US-5627028-A | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0502723-B1 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0464959-B1 | Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof | HITACHI CHEMICAL CO LTD (JP) | 1995-12-20 | — | — | EP | disclosed |
| US-5438135-A | Fluorescence analysis | HITACHI CHEMICAL COMPANY (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0284370-B1 | Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof | HITACHI CHEMICAL CO LTD (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0597389-A1 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |
| WO-1994005025-A1 | USE OF OPTICAL BRIGHTENERS AND PHTHALOCYANINES AS PHOTOSENSITIZERS | SANDOZ LTD. (CH) | 1994-03-03 | — | — | WO | disclosed |
| US-5219706-A | Naphthalocyanine derivative and production process thereof, as well as optical information recording media using the derivatives and production process thereof | HITACHI, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0502723-A2 | Water-soluble tetraazaporphins and fluorochrome for labeling | HITACHI CHEMICAL CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0284369-B1 | 5- OR 6-ALKOXYCARBONYL-2,3-DICYANONAPHTHALENES AND PROCESS FOR PRODUCTION THEREOF | Hitachi Chemical Co., Ltd. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0464959-A2 | Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof | Hitachi Chemical Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4833264-A | INTERMEDIATES FOR NAPHTHALOCYANINE DYES | HITACHI CHEMICAL CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0284369-A2 | 5- or 6-alkoxycarbonyl-2,3-dicyanonaphthalenes and process for production thereof | Hitachi Chemical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0284370-A2 | Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof | Hitachi Chemical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |