Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487 | 0.84 | — | — | |
| SCHEMBL9784696 | 0.84 | NOS3 (0.56) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL29382337 | 0.84 | — | — | |
| Hydrogen Sulfide SCHEMBL5051770 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| Hydrochloric Acid SCHEMBL1936573 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| Iodide SCHEMBL11070567 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| Bromide SCHEMBL10623431 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL29735919 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| Fluoride SCHEMBL3185683 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2CCR1CCR5 | |
| Acetonitrile SCHEMBL27689078 | 0.74 | NOS3 (0.46) | NOS3NOS1NOS2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035260-A1 | 4-aza-steroids | NOVOPHARM LIMITED | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035260-A1 | 4-aza-steroids | SRD5A2, SRD5A1, CYP17A1 | NOS3 1930/4885NOS1 1692/4885NOS2 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.