SCHEMBL7590466

SCHEMBL7590466

Cl[Zr](Cl)(Cl)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
TDP1 Q9NUW8 4/20 0.37
CYP3A4 P08684 1/20 0.37
ALDH1A1 P00352 4/20 0.35
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
HIF1A Q16665 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
CYP1A2 P05177 1/20 0.32
CA2 P00918 3/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595877 0.79 TSHR (0.39) TSHRTDP1ALDH1A1LMNABBOX1
SCHEMBL7592865 0.79 TSHR (0.39) TSHRTDP1ALDH1A1LMNABBOX1
SCHEMBL4942614 0.73 TSHR (0.35) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL7592091 0.69 ALDH1A1 (0.40) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL7592855 0.64 ALDH1A1 (0.39) TSHRTDP1ALDH1A1LMNABBOX1
SCHEMBL7595360 0.64 ALDH1A1 (0.39) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL7591543 0.64 ALDH1A1 (0.35) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL7590431 0.64 ALDH1A1 (0.35) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL28107979 0.64 ALDH1A1 (0.35) TSHRTDP1CYP3A4ALDH1A1LMNA
SCHEMBL7596714 0.64 ALDH1A1 (0.35) TSHRTDP1CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1312228-C Process for producing chemically modified fillers PPG IND OHIO INC (US) 2007-04-25 CN claimed
CN-1312229-C Process for producing chemically treated fillers PPG IND OHIO INC (US) 2007-04-25 CN claimed
CN-1374989-A Process for producing chemically treated fillers PPG IND OHIO INC (US) 2002-10-16 CN claimed
CN-1374988-A Process for producing chemically modified fillers PPG IND OHIO INC (US) 2002-10-16 CN claimed
US-20180264783-A1 Metal Foil, Metal Foil Having Release Layer, Laminated Material, Printed Wiring Board, Semiconductor Package, Electronic Device, And Method For Producing Printed Wiring Board JX NIPPON MINING & METALS CORPORATION (JP) 2018-09-20 US disclosed
US-20170362733-A1 COPPER FOIL WITH RELEASE LAYER, LAMINATED MATERIAL, METHOD FOR PRODUCING PRINTED WIRING BOARD, AND METHOD FOR PRODUCING ELECTRONIC APPARATUS JX NIPPON MINING & METALS CORPORATION (JP) 2017-12-21 US disclosed
CN-1324093-C Process for producing hydrophobic particulate inorganic oxide PPG IND OHIO INC (US) 2007-07-04 CN disclosed
CN-1312228-C Process for producing chemically modified fillers PPG IND OHIO INC (US) 2007-04-25 CN disclosed
CN-1312229-C Process for producing chemically treated fillers PPG IND OHIO INC (US) 2007-04-25 CN disclosed
EP-0694563-B1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON MITSUBISHI OIL CORP (JP) 2002-10-30 EP disclosed
CN-1374989-A Process for producing chemically treated fillers PPG IND OHIO INC (US) 2002-10-16 CN disclosed
CN-1374987-A Process for producing hydrophobic particulate inorganic oxides PPG IND OHIO INC (US) 2002-10-16 CN disclosed
EP-0745616-B1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO LTD (JP) 1999-04-07 EP disclosed
US-5780562-A GROUP 4 METAL ALKOXIDE DERIVATIVES COMPLEXED WITH GROUP 1-3 METAL ALKOXIDE DERIVATIVES, ORGANOCYCLIC COMPOUNDS HAVING CONJUGATED BONDS, ALUMOXANES, AND A SLILICA OR ALUMINA NIPPON OIL CO., LTD. (JP) 1998-07-14 US disclosed
US-5750454-A Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO., LTD. (JP) 1998-05-12 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0748823-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-18 EP disclosed
EP-0745616-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-04 EP disclosed
EP-0694563-A1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 1996-01-31 EP disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed