SCHEMBL7590431

SCHEMBL7590431

I[Zr](I)(I)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 3/20 0.32
ALOX12 P18054 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
TSHR P16473 4/20 0.32
TDP1 Q9NUW8 4/20 0.32
CA2 P00918 3/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.32
ACHE P22303 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596714 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7591543 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7592091 0.69 ALDH1A1 (0.40) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7590874 0.67 ACHE (0.50) ALDH1A1HSD17B10ALOX12HPGDALOX15
SCHEMBL28107979 0.64 ALDH1A1 (0.35) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7590466 0.64 TSHR (0.39) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7595360 0.64 ALDH1A1 (0.39) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7595877 0.64 TSHR (0.39) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7592855 0.64 ALDH1A1 (0.39) ALDH1A1HSD17B10ALOX12HPGDHIF1A
SCHEMBL7597869 0.64 ALDH1A1 (0.39) ALDH1A1HSD17B10ALOX12HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694563-B1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON MITSUBISHI OIL CORP (JP) 2002-10-30 EP disclosed
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
US-6077804-A Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 2000-06-20 US disclosed
EP-0745616-B1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO LTD (JP) 1999-04-07 EP disclosed
US-5780562-A GROUP 4 METAL ALKOXIDE DERIVATIVES COMPLEXED WITH GROUP 1-3 METAL ALKOXIDE DERIVATIVES, ORGANOCYCLIC COMPOUNDS HAVING CONJUGATED BONDS, ALUMOXANES, AND A SLILICA OR ALUMINA NIPPON OIL CO., LTD. (JP) 1998-07-14 US disclosed
US-5750454-A Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO., LTD. (JP) 1998-05-12 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0748823-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-18 EP disclosed
EP-0745616-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-04 EP disclosed
EP-0694563-A1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 1996-01-31 EP disclosed