Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033230 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL16800755 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL5554720 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL13223371 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL16582365 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL16382945 | 1.00 | SLC6A9 (0.46) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL24312219 | 0.93 | SLC6A9 (0.42) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL22599436 | 0.93 | SLC6A9 (0.42) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL22215011 | 0.93 | SLC6A9 (0.42) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 | |
| SCHEMBL16800699 | 0.93 | SIGMAR1 (0.49) | SLC6A9HSD17B10SIGMAR1KDM4ETACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998466-B1 | A PROCESS FOR THE PREPARATION OF TETRAAZAMACROCYCLES | BRACCO IMAGING SPA (IT) | 2002-10-16 | — | — | EP | claimed |
| US-5922862-A | Process for the preparation of tetraazamacrocycles | DIBRA S.P.A. (IT) | 1999-07-13 | — | — | US | disclosed |