Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594703 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2CA1CA2 | |
| SCHEMBL7590712 | 0.73 | SMN1; SMN2 (0.42) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL10538116 | 0.73 | EPHX2 (0.47) | EPHX2BTKKDM1AKMT2AMAOB | |
| SCHEMBL28453494 | 0.72 | EPHX2 (0.47) | MTNR1AMTNR1BEPHX2CA1CA2 | |
| SCHEMBL29500833 | 0.72 | EPHX2 (0.47) | MTNR1AMTNR1BEPHX2CA1CA2 | |
| SCHEMBL29500863 | 0.71 | EPHX2 (0.46) | MTNR1AMTNR1BEPHX2CA1CA2 | |
| SCHEMBL28454507 | 0.71 | EPHX2 (0.46) | MTNR1AMTNR1BEPHX2CA1CA2 | |
| SCHEMBL9824427 | 0.71 | CA1 (0.40) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8765995 | 0.71 | MTNR1A (0.62) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL10542359 | 0.71 | EPHX2 (0.43) | EPHX2CA1CA2BTKKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368573-B1 | MEASURING MYOCARDIAL FUNCTION IN MAMMAL | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2002-04-09 | — | — | US | disclosed |
| US-5063233-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0222996-B1 | 3-AMINO-DIHYDRO(1)BENZOPYRANE AND BENZOTHIOPYRANE | CIBA-GEIGY AG (CH) | 1991-05-22 | — | — | EP | disclosed |
| US-4968697-A | ADENOSINE-2 RECEPTOR AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| US-4954504-A | Hypotensive agents, psychotic disorders | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0323807-A2 | Certain 2-substituted adenosine derivatives | CIBA-GEIGY AG (CH) | 1989-07-12 | — | — | EP | disclosed |
| US-4801605-A | ANTIDEPRESSANT, NERVOUS SYSTEM DISORDERS, SEROTONIC ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0267878-A1 | N9-cyclopentyl-substituted adenine derivatives | CIBA-GEIGY AG (CH) | 1988-05-18 | — | — | EP | disclosed |
| EP-0222996-A2 | 3-Amino-dihydro(1)benzopyrane and benzothiopyrane | CIBA-GEIGY AG (CH) | 1987-05-27 | — | — | EP | disclosed |