Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516792 | 0.84 | GABBR2 (0.56) | MAPTMMEACECYP3A4POLB | |
| SCHEMBL10588247 | 0.78 | ACE (0.44) | MAPTMMEATMACECYP1A2 | |
| SCHEMBL7596100 | 0.78 | MME (0.56) | MAPTMMEATMACEHPGD | |
| SCHEMBL7471270 | 0.77 | MME (0.67) | MMEACECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10662935 | 0.75 | HPGD (0.58) | MMECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11018143 | 0.74 | ASAH1 (0.51) | MMEACEHPGDMEN1KMT2A | |
| SCHEMBL3916076 | 0.72 | CYP1A2 (0.73) | MAPTMMEACECYP1A2CYP3A4 | |
| SCHEMBL7311547 | 0.72 | CYP1A2 (0.73) | MAPTMMEACECYP1A2CYP3A4 | |
| SCHEMBL7309885 | 0.72 | CYP1A2 (0.73) | MAPTMMEACECYP1A2CYP3A4 | |
| SCHEMBL27909267 | 0.72 | ACE (0.44) | MMEACECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028248-A1 | RAPID-RELEASE MICRODISPERSIBLE ECADOTRIL PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | US | disclosed |
| EP-0914822-A1 | RAPID-RELEASE MICRODISPERSIBLE ECADOTRIL PREPARATION | Bayer Aktiengesellschaft (DE) | 1999-05-12 | — | — | EP | disclosed |