Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.56 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588247 | 0.87 | ACE (0.44) | GABBR2GABBR1MAPTMMEACE | |
| SCHEMBL27497278 | 0.85 | ITGB3 (0.41) | GABBR2GABBR1MAPTMMEACE | |
| SCHEMBL27516185 | 0.84 | CTSA (0.46) | GABBR2GABBR1FNTAFNTBALDH1A1 | |
| SCHEMBL7590758 | 0.84 | MAPT (0.46) | GABBR2GABBR1MAPTMMEACE | |
| SCHEMBL9336433 | 0.83 | GABBR2 (0.53) | GABBR2GABBR1MAPTPOLBKDM4E | |
| SCHEMBL10358939 | 0.81 | GABBR2 (0.54) | GABBR2GABBR1MAPTPOLBKDM4E | |
| SCHEMBL9732223 | 0.81 | CTSA (0.43) | MMEACE | |
| SCHEMBL27909267 | 0.80 | ACE (0.44) | GABBR2GABBR1MMEACEKMT2A | |
| SCHEMBL4172912 | 0.80 | ALOX5 (0.37) | GABBR2GABBR1MAPTMMEACE | |
| SCHEMBL503819 | 0.79 | GABBR2 (0.76) | GABBR2GABBR1MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228532-A | — | — | None | — | — | JP | disclosed |
| JP-H11228532-A | PRODUCTION OF OPTICALLY ACTIVE 2-ACETYLTHIOMETHYL-3-PHENYLPROPIONIC ACID | AJINOMOTO CO INC | 1999-08-24 | — | — | JP | disclosed |