Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561580 | 0.98 | TLR8 (0.50) | TLR8MEN1KMT2AHTTFAAH | |
| SCHEMBL16836384 | 0.93 | TLR8 (0.49) | TLR8CNR1CNR2LMNANCF1 | |
| SCHEMBL2333830 | 0.92 | NCF1 (0.51) | NCF1HDAC6HTR1AADRA1DADRA1A | |
| SCHEMBL10950611 | 0.89 | NCF1 (0.51) | TLR8MEN1KMT2ACNR1CNR2 | |
| SCHEMBL10945765 | 0.89 | NCF1 (0.51) | TLR8MEN1KMT2ACNR1CNR2 | |
| SCHEMBL19938062 | 0.88 | TLR8 (0.47) | TLR8MEN1KMT2ACNR1CNR2 | |
| SCHEMBL21834887 | 0.84 | CNR2 (0.47) | KMT2AHTTCNR1CNR2LMNA | |
| SCHEMBL21834885 | 0.84 | CNR2 (0.47) | KMT2AHTTCNR1CNR2LMNA | |
| SCHEMBL27530219 | 0.83 | TLR8 (0.41) | TLR8MEN1KMT2AHTTCNR1 | |
| SCHEMBL23716938 | 0.82 | CNR2 (0.46) | TLR8KMT2AHTTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |