SCHEMBL7590859

SCHEMBL7590859

CCC(OC(C)=O)(OC(C)=O)C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940978 0.80 GAA (0.46) GAAALDH1A1LMNAHSD17B10
SCHEMBL9704412 0.78 GAA (0.39) GAAALDH1A1LMNAHSD17B10
SCHEMBL8378234 0.77 ALDH1A1 (0.37) GAAALDH1A1LMNAHSD17B10
SCHEMBL4610366 0.76 GAA (0.38) GAAALDH1A1LMNAHSD17B10
SCHEMBL6058802 0.76 GAA (0.38) GAAALDH1A1LMNAHSD17B10
SCHEMBL6314494 0.74 GAA (0.52) GAAALDH1A1LMNAHSD17B10
SCHEMBL10570791 0.73 GAA (0.35) GAAALDH1A1LMNAHSD17B10
SCHEMBL29135299 0.73 DGAT1 (0.40) GAAALDH1A1LMNAHSD17B10
SCHEMBL25573784 0.73 GAA (0.40) GAAALDH1A1LMNAHSD17B10
SCHEMBL204648 0.70 GAA (0.41) GAAALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448442-B1 X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS AMERSHAM HEALTH AS (NO) 2002-09-10 US disclosed
US-6310243-B1 BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY NYCOMED IMAGING AS (NO) 2001-10-30 US disclosed
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US disclosed
EP-0185248-B1 POLYADDITION OR POLYCONDENSATION PRODUCTS, THEIR AQUEOUS DISPERSIONS AS WELL AS A PHOTOGRAPHIC RECORDING MATERIAL CONTAINING A PHOTOGRAPHIC COMPOUND IN THE FORM OF SUCH POLYMERIC PRODUCTS Agfa-Gevaert AG (DE) 1990-10-03 EP disclosed
US-4762777-A NONDIFFUSING AGFA-GEVAERT AG (DE) 1988-08-09 US disclosed
EP-0185248-A2 Polyaddition or polycondensation products, their aqueous dispersions as well as a photographic recording material containing a photographic compound in the form of such polymeric products Agfa-Gevaert AG (DE) 1986-06-25 EP disclosed
US-RE31512-E SISOMICIN BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1984-01-31 US disclosed
US-4235888-A SISOMYCIN-TYPE ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-25 US disclosed
EP-0007996-A1 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them BAYER AG (DE) 1980-02-20 EP disclosed