Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190834 | 0.85 | TSHR (0.57) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL17420759 | 0.83 | ALDH1A1 (0.53) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL17420751 | 0.83 | TSHR (0.46) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL30628231 | 0.83 | ALDH1A1 (0.53) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL30628279 | 0.83 | TSHR (0.46) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL30968707 | 0.81 | TSHR (0.68) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL574192 | 0.81 | TSHR (0.68) | CYP3A4CYP2D6GAATSHRMEN1 | |
| Dimethylamine SCHEMBL8210405 | 0.81 | GAA (0.53) | CYP3A4CYP2D6GAATSHRMEN1 | |
| SCHEMBL9864607 | 0.80 | ESR1 (0.52) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11610093 | 0.80 | ALDH1A1 (0.51) | CYP3A4CYP2D6GAATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007068-A1 | Piperidine derivatives and process for their production | D AMBRA THOMAS E (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007068-A1 | Piperidine derivatives and process for their production | DRD4, HRH4, DRD2 | CYP3A4 10/4885CYP2D6 264/4885GAA 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.