SCHEMBL7590961

SCHEMBL7590961

C=CCOC(CC=C)(CC(N)=O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28430072 0.84 HTT (0.35) HTTMAPTCACNA1BAPBA1
SCHEMBL5671227 0.75 MAPT (0.33) HTTMAPTCACNA1BAPBA1
SCHEMBL7695481 0.73 MAPT (0.39) HTTMAPTCACNA1BAPBA1
SCHEMBL11498754 0.73
SCHEMBL9052371 0.70 ALDH1A1 (0.34)
SCHEMBL1958586 0.69 HTT (0.40) HTT
SCHEMBL28127670 0.67 HTT (0.39) HTT
Diallyl Sulfide SCHEMBL4956576 0.66 ALOX5 (0.33)
SCHEMBL5371980 0.66 ALDH1A1 (0.34)
SCHEMBL3942986 0.66 MAPT (0.33) HTTMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245650-A2 Low foam N,N'-dialkylmalamide wetting agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-10-02 EP claimed
US-6413914-B1 AQUEOUS SOLUTIONS; REDUCING SURFACE TENSION; RENEWABLE-BASED SURFACTANTS AIR PRODUCTS AND CHEMICALS, INC. 2002-07-02 US claimed
EP-1245650-A2 Low foam N,N'-dialkylmalamide wetting agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-10-02 EP disclosed
US-6413914-B1 AQUEOUS SOLUTIONS; REDUCING SURFACE TENSION; RENEWABLE-BASED SURFACTANTS AIR PRODUCTS AND CHEMICALS, INC. 2002-07-02 US disclosed