SCHEMBL7591384

SCHEMBL7591384

NC1=NCC(C(F)(F)F)C1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 12/20 0.63
NOS2 P35228 12/20 0.63
NOS3 P29474 11/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591380 0.82 NOS3 (0.48) NOS1NOS2NOS3
SCHEMBL7597109 0.76 NOS3 (0.50) NOS1NOS2NOS3
SCHEMBL2042886 0.62 NOS3 (0.33) NOS1NOS2NOS3
SCHEMBL7599174 0.55 NOS3 (0.39) NOS1NOS2NOS3
SCHEMBL1035408 0.53 NOS3 (0.36) NOS1NOS2NOS3
SCHEMBL18060 0.53
SCHEMBL11762385 0.53 NOS3 (0.31) NOS1NOS2NOS3
SCHEMBL1447713 0.53
SCHEMBL1028934 0.51
SCHEMBL12326723 0.51 NOS3 (0.32) NOS1NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663394-B1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL CO (JP) 2002-11-13 EP disclosed
US-5498725-A Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0663394-A1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-07-19 EP disclosed