SCHEMBL7597109

SCHEMBL7597109

CC(C)(C)C1CN=C(N)C1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 16/20 0.50
NOS1 P29475 16/20 0.50
NOS2 P35228 16/20 0.50
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ANO1 Q5XXA6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327111 0.73
SCHEMBL18857800 0.67 GABRP (0.32)
Hydrochloric Acid SCHEMBL10545940 0.65
SCHEMBL4008790 0.64
SCHEMBL31706105 0.63 NOS3 (0.41) NOS3NOS1NOS2
SCHEMBL18886188 0.58
SCHEMBL24836859 0.57 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29392948 0.56
SCHEMBL24836883 0.56 NOS3 (0.36) NOS3NOS1NOS2MAPTSMN1; SMN2
SCHEMBL2691341 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663394-B1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL CO (JP) 2002-11-13 EP disclosed
US-5498725-A Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0663394-A1 Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-07-19 EP disclosed