Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821620 | 0.81 | KMT2A (0.76) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL13598032 | 0.81 | KMT2A (1.00) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL13598042 | 0.79 | USP2 (0.76) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL3984110 | 0.78 | RAB9A (0.70) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL13598035 | 0.78 | KMT2A (1.00) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL2069110 | 0.78 | KMT2A (0.78) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL13598043 | 0.78 | USP2 (0.73) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL15200787 | 0.77 | KMT2A (0.72) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL13598044 | 0.77 | KDM4E (0.70) | KDM4EKMT2AMEN1RXFP1RAB9A | |
| SCHEMBL30919345 | 0.77 | MEN1 (0.81) | KDM4EKMT2AMEN1RXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | disclosed |