Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527011 | 1.00 | IDO1 (0.36) | IDO1TDO2MRGPRX4PPARGRXRA | |
| SCHEMBL30198749 | 0.84 | PPARG (0.42) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL1070284 | 0.84 | PPARG (0.42) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL28978849 | 0.82 | PPARG (0.41) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL22771449 | 0.82 | IDO1 (0.38) | IDO1TDO2MRGPRX4PPARGRXRA | |
| SCHEMBL29515498 | 0.81 | MRGPRX4 (0.36) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL28991513 | 0.81 | MRGPRX4 (0.36) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL6291525 | 0.81 | MRGPRX4 (0.36) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL7593287 | 0.80 | MRGPRX4 (0.35) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL28307666 | 0.80 | MRGPRX1 (0.40) | MRGPRX4PPARGRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784950-A | Novel thyromimetic agents | 速通医疗公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-105612162-B | Thiazolopyrimidinones as modulators of NMDA receptor activity | 豪夫迈·罗氏有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-102066359-B | Novel heteroaryl carboxamide derivatives | HOFFMANN LA ROCHE | 2013-08-21 | — | — | CN | disclosed |
| CN-102066359-A | Novel heteroaryl carboxamide derivatives | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | disclosed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6281214-B1 | USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS | EISAI CO., LTD (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-0675118-A2 | Biphenylderivatives, process for their preparation and their use as medicaments | Eisai Co., Ltd. (JP) | 1995-10-04 | — | — | EP | disclosed |