SCHEMBL7593287

SCHEMBL7593287

OB(O)Oc1cccc(C(F)(F)F)c1C(F)(F)F.[NaH]

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.35
PPARG P37231 2/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
HSD11B1 P28845 2/20 0.33
MGLL Q99685 1/20 0.31
NOTUM Q6P988 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CA2 P00918 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
IDO1 P14902 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29515498 0.98 MRGPRX4 (0.36) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL6291525 0.98 MRGPRX4 (0.36) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL26112090 0.83 MRGPRX4 (0.34) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL30198749 0.83 PPARG (0.42) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL1070284 0.83 PPARG (0.42) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL28978849 0.81 PPARG (0.41) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL7591797 0.80 IDO1 (0.36) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL30527011 0.80 IDO1 (0.36) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL28991513 0.80 MRGPRX4 (0.36) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL28307666 0.79 MRGPRX1 (0.40) MRGPRX4PPARGRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6426396-B2 PARAPHENYLENE POLYMER PRODUCED BY REMOVING THE SUBSTITIUENTS FROM THE CYCLOHEXADIENE RING; NICKEL BASED CATALYST; ELECTROCONDUCTIVITY KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2002-07-30 US disclosed
US-20020007026-A1 POLY (CYCLIC CONJUGATED DIENE) AND PROCESS FOR PRODUCING THE SAME NAKANO MITSURU (JP) 2002-01-17 US disclosed
EP-0828768-B1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION GOODRICH CO B F (US) 2001-04-18 EP disclosed
EP-0828768-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION The B.F. Goodrich Company (US) 1998-03-18 EP disclosed
US-5677405-A COPOLYMER OF NORBORNENE-TYPE MONOMER WHICH UNDERGOES ADDITION POLYMERIZATION AND CATIONICALLY POLYMERIZABLE MONOMER THE B.F. GOODRICH COMPANY (US) 1997-10-14 US disclosed
WO-1996037529-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION THE B.F. GOODRICH COMPANY (US) 1996-11-28 WO disclosed