Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537056 | 0.80 | CCR3 (0.56) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4926363 | 0.75 | PDE7A (0.68) | PDE7AMEN1KMT2AMAPK1TSHR | |
| SCHEMBL8552311 | 0.73 | CCR3 (0.63) | ALDH1A1CCR3MAPTCXCR4ACHE | |
| Hydrochloric Acid SCHEMBL8550641 | 0.72 | CCR3 (0.61) | ALDH1A1CCR3MAPTCXCR4BCHE | |
| SCHEMBL5626341 | 0.70 | MEN1 (0.66) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL11792992 | 0.70 | LMNA (0.52) | MEN1KMT2ATSHRSSTR5ACHE | |
| SCHEMBL4491722 | 0.69 | ACHE (0.45) | CCR3CYP3A4BCHEACHE | |
| SCHEMBL8363511 | 0.68 | POLB (0.60) | PDE7ATSHRALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12116720 | 0.68 | MAPK1 (0.59) | MEN1KMT2AMAPK1TSHRUSP2 | |
| SCHEMBL12116727 | 0.68 | MAPK1 (0.59) | MEN1KMT2AMAPK1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998004546-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-02-05 | — | — | WO | disclosed |