Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720595 | 1.00 | NPC1 (0.42) | NPC1ADORA3ADORA2BLMNAMAPT | |
| SCHEMBL27911018 | 0.92 | HTT (0.39) | NPC1ADORA3LMNAMAPTCNR1 | |
| SCHEMBL14390977 | 0.91 | TDP1 (0.39) | NPC1ADORA3LMNAMAPTCNR1 | |
| SCHEMBL22216822 | 0.90 | CNR2 (0.39) | ADORA3ADORA2BLMNAMAPTCNR1 | |
| SCHEMBL1204431 | 0.84 | NPC1 (0.44) | NPC1ADORA3ADORA2BLMNAMAPT | |
| SCHEMBL1068828 | 0.82 | TLR8 (0.35) | NPC1LMNAMAPTCNR1CNR2 | |
| SCHEMBL7957044 | 0.81 | PPARG (0.43) | NPC1ADORA3ADORA2BLMNAMAPT | |
| SCHEMBL3813335 | 0.81 | NPC1 (0.50) | NPC1LMNAMAPTCNR1CNR2 | |
| SCHEMBL791340 | 0.80 | PTPN11 (0.49) | NPC1LMNAMAPTCNR1CNR2 | |
| SCHEMBL29638853 | 0.80 | PTPN11 (0.49) | NPC1LMNAMAPTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020131939-A1 | Hair protection compositions | ROCHE VITAMINS INC. | 2002-09-19 | — | — | US | disclosed |