Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22216822 | 0.90 | CNR2 (0.39) | PPARGPPARAADORA2AADORA1ADORA3 | |
| SCHEMBL14998026 | 0.86 | NPC1 (0.45) | PPARGPPARAADORA3ALOX15TSHR | |
| SCHEMBL807730 | 0.84 | MAPT (0.41) | PPARGPPARAADORA2AADORA1ADORA3 | |
| SCHEMBL13270945 | 0.82 | GPR88 (0.43) | PPARGPPARAADORA2AADORA1ADORA3 | |
| SCHEMBL26629807 | 0.81 | PPARG (0.53) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL7592006 | 0.81 | NPC1 (0.42) | ADORA3TSHRADORA2BLMNACNR2 | |
| SCHEMBL5720595 | 0.81 | NPC1 (0.42) | ADORA3TSHRADORA2BLMNACNR2 | |
| SCHEMBL8038910 | 0.81 | PPARG (0.47) | PPARGPPARAADORA2AADORA1ADORA3 | |
| SCHEMBL9635566 | 0.80 | MAPT (0.48) | ADORA2AADORA1ADORA3ALOX15TSHR | |
| SCHEMBL17472555 | 0.80 | CNR2 (0.39) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |