SCHEMBL7592011

SCHEMBL7592011

CC(=O)OCCN(C(=O)C1COC(C)(C)O1)C1=C(I)C(C)(OC(C)=O)C(I)C(OC(C)=O)=C1I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595366 0.74 HCRTR2 (0.32)
SCHEMBL7591014 0.74 RAD52 (0.31)
SCHEMBL7593766 0.67
SCHEMBL7594696 0.57 HCRTR1 (0.31)
SCHEMBL883222 0.57 CA2 (0.32)
SCHEMBL9730439 0.57 CA2 (0.32)
SCHEMBL9729738 0.55 CA2 (0.32)
SCHEMBL4361938 0.55 CA2 (0.45)
SCHEMBL14935531 0.55 CA2 (0.32)
SCHEMBL14935884 0.55 CA2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448442-B1 X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS AMERSHAM HEALTH AS (NO) 2002-09-10 US disclosed
US-6310243-B1 BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY NYCOMED IMAGING AS (NO) 2001-10-30 US disclosed
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US disclosed