Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592011 | 0.74 | — | — | |
| SCHEMBL7593766 | 0.73 | — | — | |
| SCHEMBL8378111 | 0.64 | HCRTR1 (0.32) | HCRTR2HCRTR1 | |
| SCHEMBL7594696 | 0.62 | HCRTR1 (0.31) | HCRTR2HCRTR1 | |
| SCHEMBL19080548 | 0.62 | CA2 (0.35) | HCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL354730 | 0.62 | CA2 (0.35) | HCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL17225276 | 0.61 | CA2 (0.38) | HCRTR2HCRTR1 | |
| SCHEMBL393713 | 0.59 | L3MBTL1 (0.35) | HCRTR2HCRTR1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1487144 | 0.59 | L3MBTL1 (0.35) | HCRTR2HCRTR1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL877770 | 0.59 | L3MBTL1 (0.35) | HCRTR2HCRTR1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |