Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471137 | 0.72 | AKR1C3 (0.55) | AKR1C3MAPTGAAALDH1A1KMT2A | |
| SCHEMBL30464698 | 0.72 | AKR1C3 (0.55) | AKR1C3MAPTGAAALDH1A1KMT2A | |
| SCHEMBL31727764 | 0.72 | AKR1C3 (0.55) | AKR1C3MAPTGAAALDH1A1LMNA | |
| SCHEMBL173243 | 0.72 | AKR1C3 (0.55) | AKR1C3MAPTGAAALDH1A1LMNA | |
| SCHEMBL170063 | 0.71 | AKR1C3 (0.50) | AKR1C3MAPTGAAALDH1A1LMNA | |
| SCHEMBL30560007 | 0.71 | AKR1C3 (0.50) | AKR1C3MAPTGAAALDH1A1LMNA | |
| SCHEMBL943893 | 0.71 | AKR1C3 (0.50) | AKR1C3MAPTGAAALDH1A1LMNA | |
| SCHEMBL83996 | 0.71 | AKR1C3 (0.46) | AKR1C3MAPTGAAALDH1A1LMNA | |
| Ethylene SCHEMBL27279241 | 0.70 | AKR1C3 (0.77) | AKR1C3MAPTGAAALDH1A1KMT2A | |
| Ethylene SCHEMBL11742925 | 0.70 | AKR1C3 (0.48) | AKR1C3MAPTGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232163-A1 | PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES | ALBEMARLE CORPORATION (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038333-A1 | PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES | ALBEMARLE CORPORATION (US) | 2001-05-31 | — | — | WO | disclosed |