Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.58 |
| ▸ | CTSV | O60911 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846487 | 0.86 | AHR (0.57) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17951532 | 0.80 | AR (0.54) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL28022010 | 0.79 | KIF11 (0.58) | KDM4EALDH1A1ATMAR | |
| SCHEMBL92077 | 0.78 | GAA (0.82) | POLBMEN1KMT2ANPC1GAA | |
| SCHEMBL22367061 | 0.78 | GAA (0.82) | POLBMEN1KMT2ANPC1GAA | |
| SCHEMBL29349876 | 0.78 | GAA (0.82) | POLBMEN1KMT2ANPC1GAA | |
| SCHEMBL13412901 | 0.78 | GAA (0.82) | POLBMEN1KMT2ANPC1GAA | |
| Acridone SCHEMBL29360611 | 0.78 | ALDH1A1 (1.00) | POLBMEN1KMT2ANPC1GAA | |
| Acridone SCHEMBL29641306 | 0.78 | ALDH1A1 (1.00) | POLBMEN1KMT2ANPC1GAA | |
| Acridone SCHEMBL11519726 | 0.78 | ALDH1A1 (1.00) | POLBMEN1KMT2ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705865-B1 | Photoinitiators compatible with silicones and photosensitive compositions containing the same | AGFA GEVAERT (BE) | 2002-11-06 | — | — | EP | disclosed |
| US-5776658-A | PHOTOINITIATOR CONTAINING SILICON AND KETONE GROUP | AGFA-GEVAERT AG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0705865-A1 | Photoinitiators compatible with silicones and photosensitive compositions containing the same | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-10 | — | — | EP | disclosed |