SCHEMBL7593

SCHEMBL7593

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](OC(C)=O)C[C@@]21C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 7/20 0.82
▸ PGR P06401 5/20 0.82
▸ ADORA3 P0DMS8 2/20 0.82
▸ NR1I2 O75469 2/20 0.82
▸ MAPT P10636 2/20 0.82
▸ DRD2 P14416 1/20 0.82
▸ OPRD1 P41143 1/20 0.82
▸ CYP3A4 P08684 6/20 0.70
▸ USP2 O75604 5/20 0.70
▸ HIF1A Q16665 3/20 0.70
▸ CNR1 P21554 2/20 0.70
▸ TBXA2R P21731 2/20 0.70
▸ AR P10275 1/20 0.70
▸ CHRM1 P11229 1/20 0.70
▸ LMNA P02545 3/20 0.68
▸ SMN1; SMN2 Q16637 2/20 0.68
▸ CYP2C9 P11712 2/20 0.68
▸ MLNR O43193 1/20 0.68
▸ ABCB11 O95342 1/20 0.68
▸ CYP3A5 P20815 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL8077640 0.98 NR3C1 (0.78) NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL7152754 0.96 NR3C1 (0.89) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL29395436 0.95 NR3C1 (0.84) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL11748332 0.95 NR3C1 (0.84) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL509817 0.95 NR3C1 (0.84) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL11371970 0.95 NR3C1 (0.74) NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL3362954 0.93 NR3C1 (0.82) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL1530974 0.93 NR3C1 (0.80) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL7271 0.92 NR3C1 (0.78) NR3C1PGRADORA3NR1I2MAPT
SCHEMBL20485505 0.92 NR3C1 (0.78) NR3C1PGRADORA3NR1I2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4163 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 — — EP claimed
EP-3820479-B1 METHODS TO REDUCE COMPLICATIONS OF INTRA-ARTICULAR STEROID TAIWAN LIPOSOME CO LTD (TW) 2026-03-11 — — EP claimed
US-12514820-B2 Pharmaceutical composition of intra-articular corticosteroid for pain control TAIWAN LIPOSOME CO., LTD. (TW) 2026-01-06 — — US claimed
US-12364682-B2 Use of tegaserod in preparation of anti-tumor drug QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) 2025-07-22 — — US claimed
US-20250186365-A1 COMBINATION OF ANTISPASMODIC AND OSMOTIC AGENTS FOR TOPICAL PRODUCTS AND METHOD OF USE THEREOF PRIMA INNOVATIONS, LLC 2025-06-12 — — US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 — — US claimed
WO-2025096949-A1 LIPOSOMAL COMPOSITION OF INTRA-ARTICULAR CORTICOSTEROID FOR PAIN CONTROL TAIWAN LIPOSOME COMPANY, LTD. (CN) 2025-05-08 — — WO claimed
US-20250059301-A1 Fusion Protein Construct NORTHWESTERN UNIVERSITY 2025-02-20 — — US claimed
EP-4504786-A1 ENGINEERED CD200R ANTIBODIES AND USES THEREOF MiroBio Limited (GB) 2025-02-12 — — EP claimed
US-12208104-B2 Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain TAIWAN LIPOSOME CO., LTD. (TW) 2025-01-28 — — US claimed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 — — CN claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 — — EP claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 — — WO claimed
EP-0259983-B1 The use of corticosteroids for amelioration or elimination of postoperative pain CARY GEORGE R JR (US) 1995-02-15 — — EP claimed
US-5272139-A Amelioration or elimination of postoperative pain CARY GEORGE R JR (US) 1993-12-21 — — US claimed
CN-1065996-A Reduce the method for side reaction of trichosanthes kirilowii protein SHANGHAI INST ORGANIC CHEM (CN) 1992-11-11 — — CN claimed
US-4432964-A Topical composition containing steroid in two forms released independently from polymeric carrier ALZA CORPORATION (US) 1984-02-21 — — US claimed
US-4304765-A Ocular insert housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1981-12-08 — — US claimed
US-4244942-A Creamy preparation containing steroid and process for the preparation thereof TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1981-01-13 — — US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 — — US claimed
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