Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 7/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214151 | 0.78 | TXNRD1 (0.38) | BACE1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7744841 | 0.76 | CA12 (0.35) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL11119934 | 0.74 | TXNRD1 (0.41) | MEN1KMT2ANPC1GAAMAPT | |
| Phenol SCHEMBL2748938 | 0.74 | TXNRD1 (0.51) | MEN1KMT2ANPC1MMP3BCL2L1 | |
| SCHEMBL17305949 | 0.74 | MAPT (0.39) | MAOAMAOBHSD17B3MEN1KMT2A | |
| SCHEMBL9755674 | 0.71 | TXNRD1 (0.35) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL10765128 | 0.69 | HSD17B3 (0.64) | MAOAMAOBHSD17B3BACE1PTPN1 | |
| SCHEMBL35153 | 0.69 | TXNRD1 (0.58) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL26262 | 0.68 | MAOA (1.00) | MAOAMAOBHSD17B3BACE1PTPN1 | |
| SCHEMBL901181 | 0.68 | TXNRD1 (0.56) | MAOAMAOBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898620-B1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL CO (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6432662-B1 | SOLUTION OF CHEMILUMINESCENT CYCLIC DIACYLHYDRAZIDE, AT LEAST ONE AZINE ENHANCER AND AT LEAST ONE OXIDIZING AGENT | PIERCE CHEMICAL COMPANY | 2002-08-13 | — | — | US | disclosed |
| EP-0898620-A1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL COMPANY (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997039142-A1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |