Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592900 | 0.95 | HCAR2 (0.37) | HCAR2SMN1; SMN2TSHRHCAR3PLK1 | |
| SCHEMBL7596490 | 0.90 | SMN1; SMN2 (0.37) | HCAR2SMN1; SMN2TSHRPKMMEN1 | |
| SCHEMBL29927198 | 0.83 | HCAR2 (0.47) | HCAR2SMN1; SMN2SLC37A4ESR1TAS1R3 | |
| SCHEMBL7855513 | 0.83 | HCAR2 (0.47) | HCAR2SMN1; SMN2SLC37A4ESR1TAS1R3 | |
| SCHEMBL7863490 | 0.78 | HCAR2 (0.42) | HCAR2ESR1HCAR3PLK1GPR35 | |
| SCHEMBL7653867 | 0.77 | BID (0.44) | HCAR2PLK1PLK3GPR35 | |
| SCHEMBL7654179 | 0.77 | BID (0.44) | HCAR2PLK1PLK3GPR35 | |
| SCHEMBL5076184 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRPKMMEN1KMT2A | |
| SCHEMBL5394517 | 0.73 | LDHA (0.35) | HCAR2SMN1; SMN2PKM | |
| SCHEMBL7855502 | 0.72 | LDHA (0.41) | HCAR2SMN1; SMN2ESR1METAP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968994-B1 | PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF | UBE INDUSTRIES (JP) | 2002-11-06 | — | — | EP | claimed |