Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593486 | 0.90 | HCAR2 (0.41) | SMN1; SMN2TSHRPKMHCAR2MEN1 | |
| SCHEMBL7592900 | 0.89 | HCAR2 (0.37) | SMN1; SMN2TSHRHCAR2 | |
| SCHEMBL7855502 | 0.82 | LDHA (0.41) | SMN1; SMN2LDHALDHBPKMHCAR2 | |
| SCHEMBL5394517 | 0.82 | LDHA (0.35) | SMN1; SMN2LDHALDHBPKMHCAR2 | |
| SCHEMBL10991925 | 0.76 | LDHA (0.42) | SMN1; SMN2LDHALDHBPKMHCAR2 | |
| SCHEMBL5076184 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRPKMMEN1KMT2A | |
| SCHEMBL10606616 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRMEN1KMT2ACRHBP | |
| SCHEMBL27700963 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRPKMMEN1KMT2A | |
| SCHEMBL8466685 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRMEN1KMT2ACRHBP | |
| SCHEMBL10193866 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968994-B1 | PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF | UBE INDUSTRIES (JP) | 2002-11-06 | — | — | EP | claimed |