Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466342 | 0.91 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL6466343 | 0.91 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL6531737 | 0.80 | CTSL (0.43) | CTSLCTSBCTSS | |
| SCHEMBL6061622 | 0.78 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL6468739 | 0.78 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL1701581 | 0.75 | CTSL (0.65) | CTSLCASP1CTSBCTSS | |
| SCHEMBL1796250 | 0.75 | CTSL (0.65) | CTSLCASP1CTSBCTSS | |
| SCHEMBL2487005 | 0.75 | CTSL (0.65) | CTSLCASP1CTSBCTSS | |
| SCHEMBL6467377 | 0.72 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL6139194 | 0.71 | CTSL (0.61) | CTSLCASP1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |