Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.40 |
| ▸ | CTRL | P40313 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466342 | 0.90 | CTSL (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6466343 | 0.90 | CTSL (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7593794 | 0.80 | CTSL (0.46) | CTSLCTSSCTSB | |
| SCHEMBL6468739 | 0.77 | CTSL (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6061622 | 0.77 | CTSL (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6467377 | 0.73 | CTSL (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7045967 | 0.72 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL21457995 | 0.71 | CAPN1 (0.64) | CTSLCTSBMMP3RENMMP2 | |
| SCHEMBL3844110 | 0.71 | CAPN1 (0.64) | CTSLCTSBMMP3RENMMP2 | |
| SCHEMBL21458073 | 0.70 | ANPEP (0.50) | CTSLMMP3MMP2MMP1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |