SCHEMBL7593862

SCHEMBL7593862

O=C(O)Cn1ccc(=O)nc1SCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTGDR2 Q9Y5Y4 10/20 0.53
▸ RAB9A P51151 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ PLA2G7 Q13093 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ PDE7A Q13946 1/20 0.42
▸ P2RY2 P41231 1/20 0.41
▸ P2RY4 P51582 1/20 0.41
▸ P2RY6 Q15077 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3541536 0.89 PLA2G7 (0.53) PTGDR2KMT2AMEN1PLA2G7LMNA
SCHEMBL4416151 0.74 PLA2G7 (0.64) PLA2G7
SCHEMBL3534354 0.72 PLA2G7 (0.58) KMT2AMEN1PLA2G7
SCHEMBL11344317 0.71 ALDH1A1 (0.46) SMN1; SMN2KMT2AMEN1PLA2G7LMNA
SCHEMBL3538750 0.70 PLA2G7 (0.57) PLA2G7
SCHEMBL5120452 0.69 PTGDR2 (1.00) PTGDR2RAB9ASMN1; SMN2MAPT
SCHEMBL3538417 0.69 PLA2G7 (0.55) PLA2G7
SCHEMBL3534790 0.69 PLA2G7 (0.55) PLA2G7
SCHEMBL3612929 0.69 PLA2G7 (0.58) PLA2G7
SCHEMBL4427022 0.69 PLA2G7 (0.65) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same ARTZYME BIOTECH CORPORATION (KR) 2002-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same CPN1, RNPEP, ANPEP PTGDR2 4576/4885RAB9A 2227/4885SMN1; SMN2 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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