Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594016 | 1.00 | PTGS1 (0.64) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30392676 | 0.97 | PTGS1 (0.61) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30062665 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30957417 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL31287971 | 0.87 | PTGS1 (0.54) | PTGS1GSTK1MAPTPTGS2GLO1 | |
| SCHEMBL29567569 | 0.87 | PTGS1 (0.54) | PTGS1GSTK1MAPTPTGS2GLO1 | |
| SCHEMBL24130565 | 0.86 | PTGS1 (0.48) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL24130270 | 0.86 | PTGS1 (0.48) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30834727 | 0.84 | PTGS1 (0.49) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL29350894 | 0.84 | PTGS1 (0.47) | PTGS1GSTK1ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438600-B2 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0884389-A1 | Enzyme participating in C-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5354675-A | Amidation of glycine | SHISEIDO COMPANY LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0447547-B1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO CO LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0447547-A1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO COMPANY LIMITED (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |