Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594008 | 1.00 | PTGS1 (0.64) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30392676 | 0.97 | PTGS1 (0.61) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30062665 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30957417 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL31287971 | 0.87 | PTGS1 (0.54) | PTGS1GSTK1MAPTPTGS2GLO1 | |
| SCHEMBL29567569 | 0.87 | PTGS1 (0.54) | PTGS1GSTK1MAPTPTGS2GLO1 | |
| SCHEMBL24130565 | 0.86 | PTGS1 (0.48) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL24130270 | 0.86 | PTGS1 (0.48) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL30834727 | 0.84 | PTGS1 (0.49) | PTGS1GSTK1ALDH1A1MAPTPTGS2 | |
| SCHEMBL29350894 | 0.84 | PTGS1 (0.47) | PTGS1GSTK1ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214929-A1 | SULPHONYL BENZENE DERIVATIVES AND METHODS FOR THE PREPARATION OF SULPHONYL BENZENE DERIVATIVES | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2025-07-03 | — | — | US | disclosed |
| US-20250206802-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-06-26 | — | — | US | disclosed |
| CN-116063397-B | Polypeptide targeting HER2 protein and application thereof in preparation of polypeptide coupling medicament | 中国药科大学 | 2025-05-02 | — | — | CN | disclosed |
| EP-4499119-A2 | METHODS, DEVICE, KIT AND COMPOSITIONS FOR DETECTING FELINE LUNGWORM | IDEXX Laboratories, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183934-A9 | METHODS, DEVICE, KIT AND COMPOSITIONS FOR DETECTING FELINE LUNGWORM | IDEXX LABORATORIES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240142464-A1 | METHODS, DEVICE, KIT AND COMPOSITIONS FOR DETECTING FELINE LUNGWORM | IDEXX LABORATORIES, INC. | 2024-05-02 | — | — | US | disclosed |
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230381292-A1 | Vaccines Comprising Mycobacterium Leprae Polypeptides for the Prevention, Treatment, and Diagnosis of Leprosy | INFECTIOUS DISEASE RESEARCH INSTITUTE | 2023-11-30 | — | — | US | disclosed |
| WO-2023209028-A1 | SULPHONYL BENZENE DERIVATIVES AND METHODS FOR THE PREPARATION OF SULPHONYL BENZENE DERIVATIVES | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-11-02 | — | — | WO | disclosed |
| US-11801290-B2 | Vaccines comprising Mycobacterium leprae polypeptides for the prevention, treatment, and diagnosis of leprosy | ACCESS TO ADVANCED HEALTH INSTITUTE (US) | 2023-10-31 | — | — | US | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0884389-A1 | Enzyme participating in C-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5354675-A | Amidation of glycine | SHISEIDO COMPANY LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0447547-B1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO CO LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0447547-A1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO COMPANY LIMITED (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | ITGA2B, ITGB1, ITGA1 | PTGS1 3990/4885GSTK1 3112/4885ALDH1A1 2700/4885 |
| US-20230381292-A1 | Vaccines Comprising Mycobacterium Leprae Polypeptides for the Prevention, Treatment, and Diagnosis of Leprosy | LRBA, LY96, LNPEP | PTGS1 3613/4885GSTK1 982/4885ALDH1A1 4223/4885 |
| US-20250214929-A1 | SULPHONYL BENZENE DERIVATIVES AND METHODS FOR THE PREPARATION OF SULPHONYL BENZENE DERIVATIVES | TST, BCR, ETV6 | PTGS1 3040/4885GSTK1 1844/4885ALDH1A1 2306/4885 |
| US-11801290-B2 | Vaccines comprising Mycobacterium leprae polypeptides for the prevention, treatment, and diagnosis of leprosy | LRBA, LY96, LNPEP | PTGS1 3613/4885GSTK1 982/4885ALDH1A1 4223/4885 |
| US-20250206802-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | ITGA2B, ITGB1, ITGA1 | PTGS1 3990/4885GSTK1 3112/4885ALDH1A1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.