Glycyrin

Glycyrin

SCHEMBL5327472

COc1cc2oc(=O)c(-c3ccc(O)cc3O)cc2c(OC)c1CC=C(C)C

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 8/20 0.75
▸ DYRK1A Q13627 1/20 0.66
▸ PDE4D Q08499 3/20 0.62
▸ ACHE P22303 1/20 0.58
▸ ADORA3 P0DMS8 1/20 0.52
▸ BCHE P06276 1/20 0.51
▸ MGAM O43451 1/20 0.51
▸ IDH1 O75874 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ SI P14410 1/20 0.51
▸ NFKB1 P19838 1/20 0.51
▸ FASN P49327 1/20 0.51
▸ RELA Q04206 1/20 0.51
▸ MGAM2 Q2M2H8 1/20 0.51
▸ SIRT2 Q8IXJ6 1/20 0.51
▸ TUBB4A P04350 1/20 0.49
▸ TUBB P07437 1/20 0.49
▸ TUBA3C P0DPH7 1/20 0.49
▸ TUBA1B P68363 1/20 0.49
▸ TUBA4A P68366 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycyrin SCHEMBL29388094 1.00 PTPN1 (0.75) PTPN1DYRK1APDE4DACHEADORA3
Glycycoumarin SCHEMBL29390258 0.94 PTPN1 (0.75) PTPN1DYRK1APDE4DACHEBCHE
Glycycoumarin SCHEMBL759406 0.94 PTPN1 (0.75) PTPN1DYRK1APDE4DACHEBCHE
SCHEMBL22704765 0.86 PTPN1 (1.00) PTPN1DYRK1APDE4DACHEADORA3
SCHEMBL29391195 0.86 PTPN1 (1.00) PTPN1DYRK1APDE4DACHEADORA3
Licocoumarone SCHEMBL758659 0.79 PTPN1 (1.00) PTPN1DYRK1APDE4DBCHETUBB4A
Licocoumarone SCHEMBL30220504 0.79 PTPN1 (1.00) PTPN1DYRK1APDE4DBCHETUBB4A
SCHEMBL28008322 0.78 ALOX5AP (0.59) PTPN1DYRK1APDE4DACHEADORA3
SCHEMBL15941538 0.77 PDE4D (1.00) PTPN1DYRK1APDE4DACHEADORA3
Licoricidin SCHEMBL4468990 0.76 PTPN1 (0.70) PTPN1DYRK1APDE4DACHETUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118841188-A Mining method of stomach adenocarcinoma resisting action mechanism of Sixisan and application of mining method 江苏食品药品职业技术学院 2024-10-25 — — CN claimed
US-20230276831-A1 Food/Beverage Article KIKKOMAN CORPORATION (JP) 2023-09-07 — — US claimed
EP-4176731-A1 FOOD/BEVERAGE ARTICLE Kikkoman Corporation (JP) 2023-05-10 — — EP claimed
WO-2022030443-A1 FOOD/BEVERAGE ARTICLE キッコーマン株式会社 2022-02-10 — — WO claimed
WO-2007127791-A2 NEW PHARMACOLOGICAL METHOD FOR TREATMENT OF NEUROPATHIC PAIN THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2007-11-08 — — WO claimed
US-12629350-B2 Transthyretin tetramer stabilizing agent, and preventing agent or progression suppressing agent for transthyretin amyloidosis KANEKA CORPORATION (JP) 2026-05-19 — — US disclosed
US-20250113821-A1 Methods and Compositions for Preserving Tissues and Organs MASSACHUSETTS GEN HOSPITAL (US) 2025-04-10 — — US disclosed
US-12239126-B2 Methods and compositions for preserving tissues and organs THE GENERAL HOSPITAL CORPORATION (US) 2025-03-04 — — US disclosed
CN-118841188-A Mining method of stomach adenocarcinoma resisting action mechanism of Sixisan and application of mining method 江苏食品药品职业技术学院 2024-10-25 — — CN disclosed
US-20230276831-A1 Food/Beverage Article KIKKOMAN CORPORATION (JP) 2023-09-07 — — US disclosed
US-20230276831-A1 Food/Beverage Article KIKKOMAN CORPORATION (JP) 2023-09-07 — — US disclosed
US-20230276831-A1 Food/Beverage Article KIKKOMAN CORPORATION (JP) 2023-09-07 — — US disclosed
US-7888388-B2 Peroxisome proliferator activated receptor ligand and process for producing the same KANEKA CORPORATION (JP) 2011-02-15 — — US disclosed
US-7888388-B2 Peroxisome proliferator activated receptor ligand and process for producing the same KANEKA CORPORATION (JP) 2011-02-15 — — US disclosed
US-7524975-B2 Peroxisome proliferator activated receptor ligand and process for producing the same KANEKA CORPORATION (JP) 2009-04-28 — — US disclosed
US-7524975-B2 Peroxisome proliferator activated receptor ligand and process for producing the same KANEKA CORPORATION (JP) 2009-04-28 — — US disclosed
US-20090036519-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2009-02-05 — — US disclosed
US-20090036519-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2009-02-05 — — US disclosed
WO-2007127791-A2 NEW PHARMACOLOGICAL METHOD FOR TREATMENT OF NEUROPATHIC PAIN THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2007-11-08 — — WO disclosed
US-20070249561-A1 Pharmacological method for treatment of neuropathic pain THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2007-10-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249561-A1 Pharmacological method for treatment of neuropathic pain PPARG, PPARA, CNR2 PTPN1 2713/4885DYRK1A 3268/4885PDE4D 581/4885
US-20090036519-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME PPARG, PPARA, PPARD PTPN1 945/4885DYRK1A 3340/4885PDE4D 4132/4885
US-12629350-B2 Transthyretin tetramer stabilizing agent, and preventing agent or progression suppressing agent for transthyretin amyloidosis TTR, APOB, ALB PTPN1 2066/4885DYRK1A 4337/4885PDE4D 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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