Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854741 | 0.91 | ADORA2B (0.49) | ADORA2BKMT2A | |
| SCHEMBL7849577 | 0.88 | EDNRB (0.46) | ADORA2BKMT2A | |
| SCHEMBL7850957 | 0.87 | ADORA2B (0.43) | ADORA2BKMT2A | |
| SCHEMBL7593479 | 0.86 | ADORA2B (0.39) | ADORA2BKMT2A | |
| SCHEMBL7854155 | 0.85 | ADORA2B (0.42) | ADORA2BKMT2A | |
| SCHEMBL7850919 | 0.85 | ADORA2B (0.41) | ADORA2BKMT2A | |
| SCHEMBL9285437 | 0.85 | ADORA2B (0.41) | ADORA2BKMT2A | |
| SCHEMBL7851104 | 0.84 | ADORA2B (0.40) | ADORA2BKMT2A | |
| SCHEMBL7851987 | 0.84 | ADORA2B (0.40) | ADORA2BKMT2A | |
| SCHEMBL7591161 | 0.83 | ADORA2B (0.40) | ADORA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846119-B1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE AS ENDOTHELIN ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-6140325-A | HAS ENDOTHELIN ANTAGONISTIC ACTION; FOR TREATING LIVER HYPOFUNCTION, ACUTE RENAL INSUFFICIENCY, CARDIAC INFARCTION OR LIVER INSUFFICIENCY, VASOCONSTRICTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-31 | — | — | US | disclosed |