Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.35 |
| ▸ | GNRHR | P30968 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854155 | 0.93 | ADORA2B (0.42) | ADORA2BTP53KMT2AEDNRBTRPC5 | |
| SCHEMBL7850919 | 0.93 | ADORA2B (0.41) | ADORA2BTP53KMT2AEDNRBTRPC5 | |
| SCHEMBL9288539 | 0.90 | GNRHR (0.46) | ADORA2BTP53EDNRBGNRHRPOLB | |
| SCHEMBL7851987 | 0.90 | ADORA2B (0.40) | ADORA2BTP53KMT2AEDNRBTRPC5 | |
| SCHEMBL7850957 | 0.90 | ADORA2B (0.43) | ADORA2BTP53KMT2AEDNRBTRPC5 | |
| SCHEMBL7849577 | 0.89 | EDNRB (0.46) | ADORA2BTP53KMT2AEDNRBTRPC5 | |
| SCHEMBL7594071 | 0.85 | ADORA2B (0.54) | ADORA2BKMT2A | |
| SCHEMBL7851104 | 0.84 | ADORA2B (0.40) | ADORA2BTP53KMT2ATRPC5MEN1 | |
| SCHEMBL7850334 | 0.82 | GNRHR (0.48) | ADORA2BTP53KMT2AEDNRBGNRHR | |
| SCHEMBL7594585 | 0.81 | GNRHR (0.41) | ADORA2BTP53KMT2AEDNRBTRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640606-A1 | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |