SCHEMBL7594170

SCHEMBL7594170

CCCC(CCC(C)C(=O)O)SC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.48
ACE2 Q9BYF1 1/20 0.44
CYP1A2 P05177 1/20 0.43
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BLM P54132 1/20 0.38
LTA4H P09960 1/20 0.35
GRIK1 P39086 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594632 0.82 ACE2 (0.47) GABRR1ACE2CYP1A2CHRM1AKR1A1
SCHEMBL7598680 0.81 CA2 (0.52) CHRM1AKR1A1CHRM3HTR2AHTR2C
Acetic Acid SCHEMBL15141452 0.78 GABRR1 (0.54) GABRR1ACE2CYP1A2CHRM1AKR1A1
SCHEMBL7598454 0.78 CA2 (0.53) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5747303 0.78
SCHEMBL17449760 0.78
SCHEMBL29281967 0.78 GABRR1 (0.59) GABRR1ACE2CYP1A2CHRM1AKR1A1
SCHEMBL3136028 0.78
SCHEMBL148477 0.78
Acetic Acid SCHEMBL28498892 0.78 CHRM1 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826763-B1 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 2002-11-20 EP disclosed
EP-0826763-A2 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 1998-03-04 EP disclosed