SCHEMBL7594632

SCHEMBL7594632

CCCC(CCC(C)C(=O)O)SC(=O)CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.47
GABRR1 P24046 2/20 0.47
CYP1A2 P05177 1/20 0.42
BLM P54132 1/20 0.41
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LTA4H P09960 1/20 0.38
CA2 P00918 1/20 0.35
MAPK1 P28482 1/20 0.35
GPR84 Q9NQS5 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594170 0.82 GABRR1 (0.48) ACE2GABRR1CYP1A2BLMCHRM1
SCHEMBL7598569 0.77 ALDH1A1 (0.46) TDP1GPR84FFAR1PPARD
SCHEMBL3136028 0.76
SCHEMBL148477 0.76
SCHEMBL17449760 0.76
SCHEMBL5747303 0.76
SCHEMBL29281967 0.76 GABRR1 (0.59) ACE2GABRR1CYP1A2BLMCHRM1
Hydrochloric Acid SCHEMBL10884134 0.74
SCHEMBL18093480 0.74
SCHEMBL22115933 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826763-B1 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 2002-11-20 EP claimed
EP-0826763-A2 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 1998-03-04 EP claimed
EP-0826763-B1 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 2002-11-20 EP disclosed
EP-0826763-A2 Use of 3-acylthioesters as flavouring or perfuming agents HAARMANN & REIMER GMBH (DE) 1998-03-04 EP disclosed