SCHEMBL7594359

SCHEMBL7594359

O=C(Nc1ccccc1)Nc1ccccc1C(O)CN1CCC(Cc2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 16/20 1.00
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
FAAH O00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7568196 0.88 CCR3 (1.00) CCR3
SCHEMBL6217781 0.85 CCR3 (1.00) CCR3MEN1KMT2A
SCHEMBL6704140 0.85 CCR3 (0.73) CCR3
SCHEMBL6704138 0.83 CCR3 (0.71) CCR3MEN1KMT2A
SCHEMBL7496075 0.81 CCR3 (0.69) CCR3FAAH
SCHEMBL6703659 0.80 CCR3 (1.00) CCR3
SCHEMBL7496071 0.78 CCR3 (0.80) CCR3FAAH
SCHEMBL28599359 0.74 KDM4E (0.71) CCR3MEN1KMT2AFAAH
SCHEMBL6704121 0.73 CCR3 (0.79) CCR3
SCHEMBL6705360 0.73 CCR3 (1.00) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140087-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 EP claimed
EP-1140087-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-10-10 EP claimed
WO-2000035454-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO claimed