Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162615 | 0.76 | PARP1 (0.67) | PARP1 | |
| SCHEMBL929665 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL7478192 | 0.65 | PARP1 (0.52) | KDM4EHTR2CHTR2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL2563174 | 0.62 | RAB9A (0.48) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15933532 | 0.61 | PDCD1 (0.50) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL982188 | 0.61 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11881460 | 0.60 | HTR2C (0.61) | KDM4EHTR2CHTR2AMAPTHSD17B10 | |
| SCHEMBL19305557 | 0.59 | PARP1 (0.50) | KDM4EHTR2CHTR2AMAPTHSD17B10 | |
| SCHEMBL29407494 | 0.59 | PARP1 (0.50) | KDM4EHTR2CHTR2AMAPTHSD17B10 | |
| SCHEMBL377396 | 0.59 | HTR1A (0.51) | KDM4EHTR2CHTR2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222191-A2 | BENZODIAZEPIN DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001023386-A2 | BENZODIAZEPIN DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |